Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage

Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage

The Ku heterodimer, composed of subunits Ku70 and Ku80, is known for its essential role in repairing double-stranded DNA breaks via non-homologous end joining (NHEJ). We previously identified Ku70 S155 as a novel phosphorylation site within the von Willebrand A-like (vWA) domain of Ku70 and document...

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Bibliographic Details
Main Authors: Sanna Abbasi, Laila Bayat, Caroline Schild-Poulter
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
Ku70
TRIP12
proximity-dependent biotin identification (BioID2)
phosphorylation
double-stranded breaks
proximity ligation assay
Online Access:https://www.mdpi.com/1422-0067/24/8/7041

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https://www.mdpi.com/1422-0067/24/8/7041

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