HB-EGF-induced IL-8 secretion from airway epithelium leads to lung fibroblast proliferation and migration

HB-EGF-induced IL-8 secretion from airway epithelium leads to lung fibroblast proliferation and migration

Abstract Background We have reported that heparin-binding epidermal growth factor (HB-EGF) is increased in patients with chronic obstructive pulmonary disease (COPD) and associated with collagen deposition, but the mechanisms remain unclear. In the present study, we aimed to investigated the inflamm...

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Bibliographic Details
Main Authors: Yanyu Li, Guomei Su, Yu Zhong, Zhilin Xiong, Tong Huang, Jingyun Quan, Jiewen Huang, Xiaoxia Wen, Chaole Luo, Weilin Zheng, Jinfeng Chen, Junfen Cheng, Weimin Yao, Tianwen Lai
Format: Article
Language:English
Published: BMC 2021-11-01
Series:BMC Pulmonary Medicine
Subjects:
HB-EGF
Lung fibrosis
IL-8
Airway epithelium
Online Access:https://doi.org/10.1186/s12890-021-01726-w

Internet

https://doi.org/10.1186/s12890-021-01726-w

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