The Antiviral Effects of 2-Deoxy-D-glucose (2-DG), a Dual D-Glucose and D-Mannose Mimetic, against SARS-CoV-2 and Other Highly Pathogenic Viruses

The Antiviral Effects of 2-Deoxy-D-glucose (2-DG), a Dual D-Glucose and D-Mannose Mimetic, against SARS-CoV-2 and Other Highly Pathogenic Viruses

Viral infection almost invariably causes metabolic changes in the infected cell and several types of host cells that respond to the infection. Among metabolic changes, the most prominent is the upregulated glycolysis process as the main pathway of glucose utilization. Glycolysis activation is a comm...

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Bibliographic Details
Main Authors: Beata Pająk, Rafał Zieliński, John Tyler Manning, Stanislava Matejin, Slobodan Paessler, Izabela Fokt, Mark R. Emmett, Waldemar Priebe
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
metabolic shift
viral infections
SARS-CoV-2
glycolysis
glycosylation
2-deoxy-D-glucose
Online Access:https://www.mdpi.com/1420-3049/27/18/5928

Internet

https://www.mdpi.com/1420-3049/27/18/5928

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