SCSIM: Jointly simulating correlated single-cell and bulk next-generation DNA sequencing data

SCSIM: Jointly simulating correlated single-cell and bulk next-generation DNA sequencing data

Abstract Background Recently, it has become possible to collect next-generation DNA sequencing data sets that are composed of multiple samples from multiple biological units where each of these samples may be from a single cell or bulk tissue. Yet, there does not yet exist a tool for simulating DNA...

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Bibliographic Details
Main Authors: Collin Giguere, Harsh Vardhan Dubey, Vishal Kumar Sarsani, Hachem Saddiki, Shai He, Patrick Flaherty
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Bioinformatics
Subjects:
Single-cell DNA sequencing
simulator
DNA sequencing
Hierarchical Dirichlet
Online Access:http://link.springer.com/article/10.1186/s12859-020-03550-1

Internet

http://link.springer.com/article/10.1186/s12859-020-03550-1

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