L-Tryptophan Production in Escherichia coli Improved by Weakening the Pta-AckA Pathway.

Acetate accumulation during the fermentation process of Escherichia coli FB-04, an L-tryptophan production strain, is detrimental to L-tryptophan production. In an initial attempt to reduce acetate formation, the phosphate acetyltransferase gene (pta) from E. coli FB-04 was deleted, forming strain F...

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Bibliographic Details
Main Authors: Lina Liu, Xuguo Duan, Jing Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4922666?pdf=render