Tedizolid, Faropenem, and Moxifloxacin Combination With Potential Activity Against Nonreplicating Mycobacterium tuberculosis

Tedizolid, Faropenem, and Moxifloxacin Combination With Potential Activity Against Nonreplicating Mycobacterium tuberculosis

Background:Mycobacteriumtuberculosis [Mtb] could be present in different metabolic population in the lung lesions, and nonreplicating persisters [NRP], associated with latent tuberculosis [TB], are the most difficult to kill.Objective: Test the combination of tedizolid, moxifloxacin, and faropenem f...

Full description

Bibliographic Details
Main Authors: Shashikant Srivastava, Kayle N. Cirrincione, Devyani Deshpande, Tawanda Gumbo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
special population
tuberculosis
nonreplicating persisters
regimen
hollow fiber model
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.616294/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.616294/full

Similar Items