Essential oil and polyphenolics from Thymus satureioides Coss. counteract acrylamide-induced liver toxicity through suppression of NLRP3 inflammasome/NF-κB axis

Essential oil and polyphenolics from Thymus satureioides Coss. counteract acrylamide-induced liver toxicity through suppression of NLRP3 inflammasome/NF-κB axis

Acrylamide is a carcinogenic, mutagenic and reprotoxic substance to humans through the intense oxidative stress it induces. As the liver is the most important organ in detoxifying toxic agents, we investigated here the hepatoprotective potential of Thymus satureioides aerial parts extract and their...

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Bibliographic Details
Main Authors: Mona F. Mahmoud, Rania A. Elrashidy, Heba Osama Mohammed, Badreddine Drissi, Ismail Mahdi, Mansour Sobeh
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Journal of Functional Foods
Subjects:
Thymus satureioides
Acrylamide
Liver toxicity
Collagen deposition
NLRP3 inflammasome/NF-κB axis
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623002414

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http://www.sciencedirect.com/science/article/pii/S1756464623002414

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