The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome

Abstract Nascent polypeptide chains can induce translational stalling to regulate gene expression. This is exemplified by the E. coli secretion monitor (SecM) arrest peptide that induces translational stalling to regulate expression of the downstream encoded SecA, an ATPase that co-operates with the...

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Bibliographic Details
Main Authors: Felix Gersteuer, Martino Morici, Sara Gabrielli, Keigo Fujiwara, Haaris A. Safdari, Helge Paternoga, Lars V. Bock, Shinobu Chiba, Daniel N. Wilson
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46762-2