Polymerase ζ Is Involved in Mitochondrial DNA Maintenance Processes in Concert with APE1 Activity

Mitochondrial DNA (mtDNA) damaged by reactive oxygen species (ROS) triggers so far poorly understood processes of mtDNA maintenance that are coordinated by a complex interplay among DNA repair, DNA degradation, and DNA replication. This study was designed to identify the proteins involved in mtDNA m...

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Bibliographic Details
Main Authors: Heike Katrin Schreier, Rahel Stefanie Wiehe, Miria Ricchetti, Lisa Wiesmüller
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/13/5/879