Super-resolution kinetochore tracking reveals the mechanisms of human sister kinetochore directional switching

The congression of chromosomes to the spindle equator involves the directed motility of bi-orientated sister kinetochores. Sister kinetochores bind bundles of dynamic microtubules and are physically connected through centromeric chromatin. A crucial question is to understand how sister kinetochores...

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Bibliographic Details
Main Authors: Nigel J Burroughs, Edward F Harry, Andrew D McAinsh
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/09500