Raman spectroscopy and convolutional neural networks for monitoring biochemical radiation response in breast tumour xenografts

Abstract Tumour cells exhibit altered metabolic pathways that lead to radiation resistance and disease progression. Raman spectroscopy (RS) is a label-free optical modality that can monitor post-irradiation biomolecular signatures in tumour cells and tissues. Convolutional Neural Networks (CNN) perf...

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Bibliographic Details
Main Authors: Alejandra M. Fuentes, Apurva Narayan, Kirsty Milligan, Julian J. Lum, Alex G. Brolo, Jeffrey L. Andrews, Andrew Jirasek
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28479-2