Metformin hydrochloride improves hepatic glucolipid metabolism in diabetes progression through SIRT5-mediated ECHA desuccinylation

Metformin hydrochloride improves hepatic glucolipid metabolism in diabetes progression through SIRT5-mediated ECHA desuccinylation

Abstract The management of hyperglycemia and lipid metabolism is pivotal for the treatment of type 2 diabetes mellitus (T2DM). Metformin hydrochloride (DMBG) remains the most widely prescribed medication for this condition. This study aimed to elucidate the effects and underlying mechanisms by which...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Liang Tang, Qing Sun, Jinling Luo, Suying Peng
Μορφή:	Άρθρο
Γλώσσα:	English
Έκδοση:	Nature Portfolio 2025-03-01
Σειρά:	Scientific Reports
Θέματα:	Metformin hydrochloride Hyperglycemia Lipid metabolism Desuccinylation ECHA
Διαθέσιμο Online:	https://doi.org/10.1038/s41598-025-92716-z

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