Human cardiovascular disease model predicts xanthine oxidase inhibitor cardiovascular risk.

Some health concerns are often not identified until late into clinical development of drugs, which can place participants and patients at significant risk. For example, the United States Food and Drug Administration (FDA) labeled the xanthine oxidase inhibitor febuxostat with a"boxed" warn...

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Bibliographic Details
Main Authors: Ryan E Feaver, M Scott Bowers, Banumathi K Cole, Steve Hoang, Mark J Lawson, Justin Taylor, Brian D LaMoreaux, Lin Zhao, Brad R Henke, Brian A Johns, Andrew C Nyborg, Brian R Wamhoff, Robert A Figler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0291330&type=printable