Thoracic Dorsal Root Ganglion Application of Resiniferatoxin Reduces Myocardial Ischemia-Induced Ventricular Arrhythmias

Thoracic Dorsal Root Ganglion Application of Resiniferatoxin Reduces Myocardial Ischemia-Induced Ventricular Arrhythmias

Background: A myocardial ischemia/reperfusion (IR) injury activates the transient receptor potential vanilloid 1 (TRPV1) dorsal root ganglion (DRG) neurons. The activation of TRPV1 DRG neurons triggers the spinal dorsal horn and the sympathetic preganglionic neurons in the spinal intermediolateral c...

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Bibliographic Details
Main Authors: Tomoki Yamaguchi, Siamak Salavatian, Yuki Kuwabara, Abigail Hellman, Bradley K. Taylor, Kimberly Howard-Quijano, Aman Mahajan
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Biomedicines
Subjects:
neuromodulation
myocardial ischemia
cardiac arrhythmias
deafferentation
autonomic nervous system
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Online Access:https://www.mdpi.com/2227-9059/11/10/2720

Internet

https://www.mdpi.com/2227-9059/11/10/2720

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