Blood Bacteria-Free DNA in Septic Mice Enhances LPS-Induced Inflammation in Mice through Macrophage Response

Blood Bacteria-Free DNA in Septic Mice Enhances LPS-Induced Inflammation in Mice through Macrophage Response

Although bacteria-free DNA in blood during systemic infection is mainly derived from bacterial death, translocation of the DNA from the gut into the blood circulation (gut translocation) is also possible. Hence, several mouse models with experiments on macrophages were conducted to explore the sourc...

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Bibliographic Details
Main Authors: Warerat Kaewduangduen, Peerapat Visitchanakun, Wilasinee Saisorn, Ariya Phawadee, Charintorn Manonitnantawat, Chirapas Chutimaskul, Paweena Susantitaphong, Patcharee Ritprajak, Naraporn Somboonna, Thanya Cheibchalard, Dhammika Leshan Wannigama, Patipark Kueanjinda, Asada Leelahavanichkul
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
sepsis
bacterial DNA
LPS
blood microbiome analysis
cecal ligation and puncture
Online Access:https://www.mdpi.com/1422-0067/23/3/1907

Internet

https://www.mdpi.com/1422-0067/23/3/1907

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