Transcriptomic changes associated with PCK1 overexpression in hepatocellular carcinoma cells detected by RNA-seq

Transcriptomic changes associated with PCK1 overexpression in hepatocellular carcinoma cells detected by RNA-seq

Phosphoenolpyruvate carboxykinase 1 (PCK1), a step limiting enzyme of gluconeogenesis, is downregulated in hepatocellular carcinoma (HCC). Overexpression of PCK1 has been shown to suppress hepatoma cell growth, but the underlying mechanism remains unclear. We used recombinant adenovirus overexpressi...

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Bibliographic Details
Main Authors: Jin Xiang, Yuhong Zhang, Lin Tuo, Rui Liu, Dongmei Gou, Li Liang, Chang Chen, Jie Xia, Ni Tang, Kai Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2020-03-01
Series:Genes and Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304219300200

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http://www.sciencedirect.com/science/article/pii/S2352304219300200

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