Potassium Dehydroandrograpolide Succinate Targets NRP1 Mediated VEGFR2/VE-Cadherin Signaling Pathway to Promote Endothelial Barrier Repair

Potassium Dehydroandrograpolide Succinate Targets NRP1 Mediated VEGFR2/VE-Cadherin Signaling Pathway to Promote Endothelial Barrier Repair

Impairment of vascular endothelial integrity is associated with various vascular diseases. Our previous studies demonstrated that andrographolide is critical to maintaining gastric vascular homeostasis, as well as to regulating pathological vascular remodeling. Potassium dehydroandrograpolide succin...

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Bibliographic Details
Main Authors: Zheng Wang, Xiao Wu, Jiali Li, Qiru Guo, Zhong Jin, Hongfei Li, Bing Liang, Wangming Hu, Huan Xu, Liangqin Shi, Lan Yang, Yong Wang
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
PDA
NRP1
VEGF signaling pathway
VE-Cad
endothelial barrier
pathological vascular remodeling
Online Access:https://www.mdpi.com/1422-0067/24/4/3096

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https://www.mdpi.com/1422-0067/24/4/3096

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