DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation

GATA transcription factors regulate transcription during development and differentiation by recognizing distinct GATA sites with a tandem of two conserved zinc fingers, and by mediating long-range DNA looping. However, the molecular basis of these processes is not well understood. Here, we determine...

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Bibliographic Details
Main Authors: Yongheng Chen, Darren L. Bates, Raja Dey, Po-Han Chen, Ana Carolina Dantas Machado, Ite A. Laird-Offringa, Remo Rohs, Lin Chen
Format: Article
Language:English
Published: Elsevier 2012-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712003634