Tauroursodeoxycholic Acid Decreases Keloid Formation by Reducing Endoplasmic Reticulum Stress as Implicated in the Pathogenesis of Keloid

Tauroursodeoxycholic Acid Decreases Keloid Formation by Reducing Endoplasmic Reticulum Stress as Implicated in the Pathogenesis of Keloid

Keloids are a common form of pathologic wound healing and are characterized by an excessive production of extracellular matrix. This study examined the major contributing mechanism of human keloid pathogenesis using transcriptomic analysis. We identified the upregulation of mitochondrial oxidative s...

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Bibliographic Details
Main Authors: Sunje Kim, Seong Eun Lee, Shinae Yi, Sangmi Jun, Yoon-Sun Yi, Harsha Nagar, Cuk-Seong Kim, Chungmin Shin, Min-Kyung Yeo, Yea Eun Kang, Sang-Ha Oh
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
tauroursodeoxycholic acid
TUDCA
endoplasmic reticulum stress
ER stress
mitochondria
keloid
Online Access:https://www.mdpi.com/1422-0067/22/19/10765

Internet

https://www.mdpi.com/1422-0067/22/19/10765

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