In vitro assembly of the Rous Sarcoma Virus capsid protein into hexamer tubes at physiological temperature

Abstract During a proteolytically-driven maturation process, the orthoretroviral capsid protein (CA) assembles to form the convex shell that surrounds the viral genome. In some orthoretroviruses, including Rous Sarcoma Virus (RSV), CA carries a short and hydrophobic spacer peptide (SP) at its C-term...

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Bibliographic Details
Main Authors: Soumeya A. Jaballah, Graham D. Bailey, Ambroise Desfosses, Jaekyung Hyun, Alok K. Mitra, Richard L. Kingston
Format: Article
Language:English
Published: Nature Portfolio 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02060-0