Novel Library of Selenocompounds as Kinase Modulators

Although the causes of cancer lie in mutations or epigenic changes at the genetic level, their molecular manifestation is the dysfunction of biochemical pathways at the protein level. The 518 protein kinases encoded by the human genome play a central role in various diseases, a fact that has encoura...

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Bibliographic Details
Main Authors: Carmen Sanmartín, Juan Antonio Palop, Alfonso Calvo, Elena Ibáñez, Daniel Plano
Format: Article
Language:English
Published: MDPI AG 2011-07-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/8/6349/