Group 3 Innate Lymphoid Cells Exacerbate Lupus Nephritis by Promoting B Cell Activation in Kidney Ectopic Lymphoid Structures

Group 3 Innate Lymphoid Cells Exacerbate Lupus Nephritis by Promoting B Cell Activation in Kidney Ectopic Lymphoid Structures

Abstract Group 3 innate lymphoid cells (ILC3s) represent a new population in immune regulation, yet their role in lupus nephritis (LN) remains elusive. In the present work, systemic increases in ILC3s, particularly in the kidney, are observed to correlate strongly with disease severity in both human...

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Bibliographic Details
Main Authors: Feng Li, Zhou Liang, Haojie Zhong, Xinrong Hu, Ziwen Tang, Changjian Zhu, Jiani Shen, Xu Han, Ruoni Lin, Ruilin Zheng, Ruihan Tang, Huajing Peng, Xunhua Zheng, Chengqiang Mo, Peisong Chen, Xin Wang, Qiong Wen, Jianbo Li, Xi Xia, Hongjian Ye, Yagui Qiu, Jianwen Yu, Dongying Fu, Jiaqi Liu, Rong Wang, Huixin Xie, Yun Guo, Xiaoyan Li, Jinjin Fan, Qinghua Liu, Haiping Mao, Wei Chen, Yi Zhou
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Advanced Science
Subjects:
B cells
ectopic lymphoid structures
group 3 innate lymphoid cells
lupus nephritis
Online Access:https://doi.org/10.1002/advs.202302804

Internet

https://doi.org/10.1002/advs.202302804

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