Did Homocysteine Take Part in the Start of the Synthesis of Peptides on the Early Earth?

Unlike its shorter analog, cysteine, and its methylated derivative, methionine, homocysteine is not today a proteinogenic amino acid. However, this thiol containing amino acid is capable of forming an activated species intramolecularly. Its thiolactone could have made it an interesting molecular bui...

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Bibliographic Details
Main Authors: Sparta Youssef-Saliba, Anne Milet, Yannick Vallée
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/4/555