Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome

Obesity enhances the risk of developing myelodysplastic syndromes. However, the effect of obesity on survival is unclear. Obese people present with monocytosis due to inflammatory signals emanating from obese adipose tissue. We hypothesized that obesity-induced myelopoiesis would promote the transit...

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Những tác giả chính: Michael J. Kraakman, Helene L. Kammoun, Dragana Dragoljevic, Annas Al-Sharea, Man K.S. Lee, Michelle C. Flynn, Christian J. Stolz, Andrew A. Guirguis, Graeme I. Lancaster, Jaye Chin-Dusting, David J. Curtis, Andrew J. Murphy
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Ferrata Storti Foundation 2018-04-01
Loạt:Haematologica
Truy cập trực tuyến:https://haematologica.org/article/view/8413