New Monoterpenoid Indole Alkaloids from <i>Tabernaemontana crassa</i> Inhibit <i>β</i>-Amyloid42 Production and Phospho-Tau (Thr217)

Eleven monoterpenoid indole alkaloids, including three new ones, tabercrassines A–C (<b>1</b>–<b>3</b>), were isolated from the seeds of <i>Tabernaemontana crassa</i>. Tabercrassine A (<b>1</b>) is an ibogan–ibogan-type bisindole alkaloid which is form...

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Bibliographic Details
Main Authors: Sheng Li, Ling-Ling Han, Ke-Pu Huang, Ye-Han Ma, Ling-Li Guo, Yarong Guo, Xiaoqian Ran, Yong-Gang Yao, Xiao-Jiang Hao, Rongcan Luo, Yu Zhang
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/2/1487