Immunogenicity when utilizing adenovirus serotype 4 and 5 vaccines expressing circumsporozoite protein in naïve and Adenovirus (Ad5) immune mice

<p>Abstract</p> <p>Background</p> <p>Induction of potent long lasting effector T cell responses against liver stage malaria antigens strongly correlates with protection from malaria. While Adenovirus serotype 5 (Ad5) based malaria vaccine platforms have the ability to i...

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Bibliographic Details
Main Authors: Schuldt Nathaniel J, Aldhamen Yasser A, Godbehere-Roosa Sarah, Seregin Sergey S, Kousa Youssef A, Amalfitano Andrea
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Malaria Journal
Subjects:
Online Access:http://www.malariajournal.com/content/11/1/209