Discovering the mechanism of action of drugs with a sparse explainable networkResearch in context
Summary: Background: Although Deep Neural Networks (DDNs) have been successful in predicting the efficacy of cancer drugs, the lack of explainability in their decision-making process is a significant challenge. Previous research proposed mimicking the Gene Ontology structure to allow for interpreta...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-09-01
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Series: | EBioMedicine |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S235239642300333X |