4-Isobutylmethcathinone—A Novel Synthetic Cathinone with High In Vitro Cytotoxicity and Strong Receptor Binding Preference of Enantiomers

4-Isobutylmethcathinone—A Novel Synthetic Cathinone with High In Vitro Cytotoxicity and Strong Receptor Binding Preference of Enantiomers

New psychoactive substances and among them synthetic cathinones represent a significant threat to human health globally. However, within such a large pool of substances derived from a natural compound ((<i>S</i>)-cathinone), substances with important pharmaceutical uses can be identified...

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Bibliographic Details
Main Authors: Martin Paškan, Silvie Rimpelová, Vladimíra Svobodová Pavlíčková, Dita Spálovská, Vladimír Setnička, Martin Kuchař, Michal Kohout
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceuticals
Subjects:
synthetic cathinones
cytotoxicity
chiral drugs
chiral separation
neurotoxicity
enantiomer-selective binding to receptors
Online Access:https://www.mdpi.com/1424-8247/15/12/1495

Internet

https://www.mdpi.com/1424-8247/15/12/1495

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