mRNA-1273 boost after BNT162b2 vaccination generates comparable SARS-CoV-2-specific functional responses in naïve and COVID-19-recovered individuals

mRNA-1273 boost after BNT162b2 vaccination generates comparable SARS-CoV-2-specific functional responses in naïve and COVID-19-recovered individuals

IntroductionCOVID-19 vaccines based on mRNA have represented a revolution in the biomedical research field. The initial two-dose vaccination schedule generates potent humoral and cellular responses, with a massive protective effect against severe COVID-19 and death. Months after this vaccination, le...

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Main Authors: Roberto Lozano-Rodríguez, José Avendaño-Ortíz, Verónica Terrón, Karla Montalbán-Hernández, José Casalvilla-Dueñas, Marta Bergón-Gutiérrez, Pablo Mata-Martínez, Alejandro Martín-Quirós, Miguel Ángel García-Garrido, Álvaro del Balzo-Castillo, María Peinado, Laura Gómez, Irene Llorente-Fernández, Gema Martín-Miguel, Carmen Herrero-Benito, Lissette López-Morejón, Carmen Vela-Olmo, Carolina Cubillos-Zapata, Eduardo López-Collazo, Carlos del Fresno
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
mRNA vaccine
COVID-19 booster
SARS-CoV-2-specific
naïve
recovered from COVID-19
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1136029/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1136029/full

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