Study on the secondary structure and hydration effect of human serum albumin under acidic pH and ethanol perturbation with IR/NIR spectroscopy

Human serum albumin (HSA) is the most abundant protein in plasma and plays an essential physiological role in the human body. Ethanol precipitation is the most widely used way to obtain HSA, and pH and ethanol are crucial factors affecting the process. In this study, infrared (IR) spectroscopy and n...

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Bibliographic Details
Main Authors: Hui Zhang, Mengying Liang, Shuangshuang Li, Mengyin Tian, Xiaoying Wei, Bing Zhao, Haowei Wang, Qin Dong, Hengchang Zang
Format: Article
Language:English
Published: World Scientific Publishing 2023-07-01
Series:Journal of Innovative Optical Health Sciences
Subjects:
Online Access:https://www.worldscientific.com/doi/10.1142/S1793545822500407