Evaluation of single-strain Prevotella histicola on KLH-driven immune responses in healthy volunteers: A randomized controlled trial with EDP1815

Evaluation of single-strain Prevotella histicola on KLH-driven immune responses in healthy volunteers: A randomized controlled trial with EDP1815

Introduction: EDP1815 is a single-strain of Prevotella histicola with preclinical immunomodulatory properties. The aim of this study was to evaluate pharmacodynamic effects of EDP1815 on the immune response following immunization with keyhole limpet hemocyanin (KLH) and dermal rechallenge. Methods:...

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Bibliographic Details
Main Authors: Mahdi Saghari, Pim Gal, Hendrika W. Grievink, Erica S. Klaassen, Ahnjili Zhuparris, Andrea Itano, Mark Bodmer, Duncan McHale, Matthijs Moerland
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Medicine in Microecology
Subjects:
Delayed-type hypersensitivity
Gastrointestinal microbiome
Immune system diseases
Keyhole limpet hemocyanin
Late-phase skin reaction
Prevotella histicola
Online Access:http://www.sciencedirect.com/science/article/pii/S2590097823000137

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http://www.sciencedirect.com/science/article/pii/S2590097823000137

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