Transdermal Delivery of High Molecular Weight Antibiotics to Deep Tissue Infections via Droplette Micromist Technology Device (DMTD)

Transdermal Delivery of High Molecular Weight Antibiotics to Deep Tissue Infections via Droplette Micromist Technology Device (DMTD)

Wound infection by multidrug-resistant (MDR) bacteria is a major disease burden. Systemic administration of broad-spectrum antibiotics colistin methanesulfonate (CMS) and vancomycin are the last lines of defense against deep wound infections by MDR bacteria. However, systemic administration of CMS a...

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Bibliographic Details
Main Authors: Lakshmi Pulakat, Howard H. Chen, Madhavi P. Gavini, Lauren A. Ling, Yinian Tang, Alexander Mehm, Gregory L. Martin, Corinna N. Beale, Brian P. Mooney, Hongmin Sun
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceutics
Subjects:
transdermal delivery
Droplette micromist technology device (DMTD)
multidrug resistant bacteria
colistin methanesulfonate
vancomycin
<i>E. coli</i>
Online Access:https://www.mdpi.com/1999-4923/14/5/976

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https://www.mdpi.com/1999-4923/14/5/976

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