Isolation, purification, and full NMR assignments of cyclopamine from <it>Veratrum californicum</it>

<p>Abstract</p> <p>Background</p> <p>The Hedgehog signaling pathway is essential for embryogenesis and for tissue homeostasis in the adult. However, it may induce malignancies in a number of tissues when constitutively activated, and it may also have a role in other for...

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Bibliographic Details
Main Authors: Gallien Thomas N, Bearden Daniel W, Moeller Peter D, Rushing James W, Brunsfeld Pam, Oatis John E, Cooper George
Format: Article
Language:English
Published: BMC 2008-06-01
Series:Chemistry Central Journal
Online Access:http://journal.chemistrycentral.com/content/2/1/12