Interleukin 17 enhances bone morphogenetic protein-2-induced ectopic bone formation

Interleukin 17 enhances bone morphogenetic protein-2-induced ectopic bone formation

Abstract Interleukin 17 (IL-17) stimulates the osteogenic differentiation of progenitor cells in vitro through a synergy with bone morphogenetic protein (BMP)-2. This study investigates whether the diverse responses mediated by IL-17 in vivo also lead to enhanced BMP-2-induced bone formation. Since...

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Bibliographic Details
Main Authors: M. Croes, M. C. Kruyt, W. M. Groen, K. M. A. van Dorenmalen, W. J. A. Dhert, F. C. Öner, J. Alblas
Format: Article
Language:English
Published: Nature Portfolio 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25564-9

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https://doi.org/10.1038/s41598-018-25564-9

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