Cardiac Myocyte‐Specific Overexpression of FASTKD1 Prevents Ventricular Rupture After Myocardial Infarction

Background The mitochondrial mRNA‐binding protein FASTKD1 (Fas‐activated serine/threonine [FAST] kinase domain–containing protein 1) protects myocytes from oxidative stress in vitro. However, the role of FASTKD1 in the myocardium in vivo is unknown. Therefore, we developed cardiac‐specific FASTKD1 t...

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Bibliographic Details
Main Authors: Kurt D. Marshall, Paula J. Klutho, Lihui Song, Rajika Roy, Maike Krenz, Christopher P. Baines
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.122.025867