Dynamics of RNA Polymerase II Pausing and Bivalent Histone H3 Methylation during Neuronal Differentiation in Brain Development

During cellular differentiation, genes important for differentiation are expected to be silent in stem/progenitor cells yet can be readily activated. RNA polymerase II (Pol II) pausing and bivalent chromatin marks are two paradigms suited for establishing such a poised state of gene expression; howe...

Полное описание

Библиографические подробности
Главные авторы: Jiancheng Liu, Xiwei Wu, Heying Zhang, Gerd P. Pfeifer, Qiang Lu
Формат: Статья
Язык:English
Опубликовано: Elsevier 2017-08-01
Серии:Cell Reports
Предметы:
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S2211124717310252