Side-by-side comparison of recombinant human glutathione peroxidases identifies overlapping substrate specificities for soluble hydroperoxides

Five out of eight human glutathione peroxidases (GPXs) are selenoproteins, representing proteins that contain selenium as part of the amino acid selenocysteine. The GPXs are important for reducing hydroperoxides in a glutathione-consuming manner and thus regulate cellular redox homeostasis. GPX1, GP...

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Bibliographic Details
Main Authors: Maria Schwarz, Alina Löser, Qing Cheng, Mareike Wichmann-Costaganna, Patrick Schädel, Oliver Werz, Elias SJ. Arnér, Anna P. Kipp
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722003652