p53 amyloid aggregation in cancer: function, mechanism, and therapy

Abstract Similar to neurodegenerative diseases, the concept that tumors are prion like diseases has been proposed in recent years. p53, the most well-known tumor suppressor, has been extensively studied for its expression, mutation, and function in various tumors. Currently, an interesting phenomeno...

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Bibliographic Details
Main Authors: Jingzhi Li, Ming Guo, Lin Chen, Zhuchu Chen, Ying Fu, Yongheng Chen
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Experimental Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s40164-022-00317-7