PD-L1 and PD-L2 expression in the tumor microenvironment including peritumoral tissue in primary central nervous system lymphoma

Abstract Background The prevalence of programmed death-ligand 1 (PD-L1) and PD-L2 expression on tumor cells and tumor-infiltrating immune cells in primary central nervous system lymphoma (PCNSL) remains unclear. In the present study, we analyzed needle biopsy and craniotomy specimens of patients wit...

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Bibliographic Details
Main Authors: Motomasa Furuse, Hiroko Kuwabara, Naokado Ikeda, Yasuhiko Hattori, Tomotsugu Ichikawa, Naoki Kagawa, Kenichiro Kikuta, Sho Tamai, Mitsutoshi Nakada, Toshihiko Wakabayashi, Masahiko Wanibuchi, Toshihiko Kuroiwa, Yoshinobu Hirose, Shin-Ichi Miyatake
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-020-06755-y