Hypertension and hyperglycemia synergize to cause incipient renal tubular alterations resulting in increased NGAL urinary excretion in rats.

Hypertension and hyperglycemia synergize to cause incipient renal tubular alterations resulting in increased NGAL urinary excretion in rats.

<h4>Background</h4>Hypertension and diabetes are the two leading causes of chronic kidney disease (CKD) eventually leading to end stage renal disease (ESRD) and the need of renal replacement therapy. Mortality among CKD and ESRD patients is high, mostly due to cardiovascular events. New...

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Main Authors: Ana M Blázquez-Medela, Omar García-Sánchez, Víctor Blanco-Gozalo, Yaremi Quiros, María J Montero, Carlos Martínez-Salgado, José M López-Novoa, Francisco J López-Hernández
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25148248/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25148248/pdf/?tool=EBI

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