Endocardial role in arrhythmias induced by acute ventricular stretch and the involvement of Purkinje fibres, in isolated rat hearts

Purkinje fibres (PFs) play an important role in some ventricular arrhythmias and acute ventricular stretch can evoke mechanically-induced arrhythmias. We tested whether PFs and specifically TRPM4 channels, play a role in these mechanically-induced arrhythmias. Pseudo-ECGs and left ventricular (LV) a...

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Bibliographic Details
Main Authors: Miriam Hurley, Sarbjot Kaur, Richard Walton, Amelia Power, Michel Haïssaguerre, Olivier Bernus, Marie-Louise Ward, Ed White
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Physiology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2665944123000019