Enhancer/gene relationships: Need for more reliable genome-wide reference sets

Differences in cells’ functions arise from differential activity of regulatory elements, including enhancers. Enhancers are cis-regulatory elements that cooperate with promoters through transcription factors to activate the expression of one or several genes by getting physically close to them in th...

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Bibliographic Details
Main Authors: Tristan Hoellinger, Camille Mestre, Hugues Aschard, Wilfried Le Goff, Sylvain Foissac, Thomas Faraut, Sarah Djebali
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Bioinformatics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2023.1092853/full