Estrogen and Androgen Blockade for Advanced Prostate Cancer in the Era of Precision Medicine

Estrogen and Androgen Blockade for Advanced Prostate Cancer in the Era of Precision Medicine

Androgen deprivation therapy (ADT) has been widely prescribed for patients with advanced prostate cancer (PC) to control key signaling pathways via androgen receptor (AR) and AR-collaborative transcriptional factors; however, PC gradually acquires a lethal phenotype and results in castration-resista...

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Bibliographic Details
Main Authors: Tetsuya Fujimura, Kenichi Takayama, Satoru Takahashi, Satoshi Inoue
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Cancers
Subjects:
prostate cancer
androgen receptor
estrogen-related receptor
stem cell
androgen deprivation therapy (ADT)
selective estrogen receptor modulators (SERMs)
personalized medicine
precision medicine
Online Access:http://www.mdpi.com/2072-6694/10/2/29

Internet

http://www.mdpi.com/2072-6694/10/2/29

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