Conversion of silent synapses to AMPA receptor-mediated functional synapses in human cortical organoids

Despite the crucial role of synaptic connections and neural activity in the development and organization of cortical circuits, the mechanisms underlying the formation of functional synaptic connections in the developing human cerebral cortex remain unclear. We investigated the development of α-amino...

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Bibliographic Details
Main Authors: Masatoshi Nishimura, Tomoki Kodera, Shota Adachi, Akinori Y. Sato, Ryosuke F. Takeuchi, Hiroshi Nonaka, Itaru Hamachi, Fumitaka Osakada
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Neuroscience Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0168010224001627