Enhancing the anticancer effects of 5-fluorouracil: Current challenges and future perspectives

5-Flurouracil (5-FU), a pyrimidine analog, was originally designed to prevent tumor cell growth. However, since the identification of its tumor inhibitory activity in 1957, substantial evidence has demonstrated that 5-FU could also harness the host immune system to prevent cancer progression. 5-FU s...

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Bibliographic Details
Main Authors: François Ghiringhelli, Lionel Apetoh
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Biomedical Journal
Subjects:
Online Access:http://www.biomedj.org/article.asp?issn=2319-4170;year=2015;volume=38;issue=2;spage=111;epage=116;aulast=Ghiringhelli