Inactivation of Tumor Suppressor CYLD Inhibits Fibroblast Reprogramming to Pluripotency

Inactivation of Tumor Suppressor CYLD Inhibits Fibroblast Reprogramming to Pluripotency

<i>CYLD</i> is a tumor suppressor gene coding for a deubiquitinating enzyme that has a critical regulatory function in a variety of signaling pathways and biological processes involved in cancer development and progression, many of which are also key modulators of somatic cell reprogramm...

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Bibliographic Details
Main Authors: Nikolaos Bekas, Martina Samiotaki, Maria Papathanasiou, Panagiotis Mokos, Athanasios Pseftogas, Konstantinos Xanthopoulos, Dimitris Thanos, George Mosialos, Dimitra Dafou
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
CYLD
somatic cell reprogramming
MET
EMT
ECM organization
TGF-beta
Online Access:https://www.mdpi.com/2072-6694/15/20/4997

Internet

https://www.mdpi.com/2072-6694/15/20/4997

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