Severe hearing loss and outer hair cell death in homozygous Foxo3 knockout mice after moderate noise exposure

Abstract Noise induced hearing loss (NIHL) is a disease that affects millions of Americans. Identifying genetic pathways that influence recovery from noise exposure is an important step forward in understanding NIHL. The transcription factor Foxo3 integrates the cellular response to oxidative stress...

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Bibliographic Details
Main Authors: Felicia Gilels, Stephen T. Paquette, Holly J. Beaulac, Anwen Bullen, Patricia M. White
Format: Article
Language:English
Published: Nature Portfolio 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01142-3