DRAM1 regulates autophagy flux through lysosomes.

We have previously reported that the mitochondria inhibitor 3-nitropropionic acid (3-NP), induces the expression of DNA damage-regulated autophagy modulator1 (DRAM1) and activation of autophagy in rat striatum. Although the role of DRAM1 in autophagy has been previously characterized, the detailed m...

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Bibliographic Details
Main Authors: Xing-Ding Zhang, Lin Qi, Jun-Chao Wu, Zheng-Hong Qin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3656954?pdf=render