Novel action of apolipoprotein E (ApoE): ApoE isoform specifically inhibits lipid-particle-mediated cholesterol release from neurons

<p>Abstract</p> <p>Background</p> <p>Since the majority of apolipoprotein E (apoE) existing in the cerebrospinal fluid is associated with high-density lipoprotein (HDL), one should focus on the role of the apoE-HDL complex rather than on that of free apoE in cholesterol...

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Bibliographic Details
Main Authors: Fujita Shinobu C, Kobayashi Mariko, Handa Tetsurou, Morita Shin-ya, Gong Jian-Sheng, Yanagisawa Katsuhiko, Michikawa Makoto
Format: Article
Language:English
Published: BMC 2007-05-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/2/1/9