Synthesis and anticancer properties of celastrol derivatives involved in the inhibition of VEGF

In this study, fourteen celastrol derivatives (1–14) were synthesised by esterification of celastrol at the 29th position. The in vitro anticancer activity of them was determined by the MTT assay. All the synthetic compounds showed significant antiproliferative activity against six cancer cells, wit...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Mingxia Song, Jiantao Wen, Yi Hua, Yangnv Zhu, Qishan Xia, Qiaoyue Guo, Yiqin Luo, Xianqing Deng, Yushan Huang
Format: Artykuł
Język:English
Wydane: Taylor & Francis Group 2023-12-01
Seria:Journal of Enzyme Inhibition and Medicinal Chemistry
Hasła przedmiotowe:
Dostęp online:https://www.tandfonline.com/doi/10.1080/14756366.2023.2238137